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Preliminary studies suggest that gabapentin is associated with α 2 -δ-subunit of voltage-dependent calcium channels and inhibits the flow of calcium ions, which plays an important role in the onset of neuropathic pain.Other mechanisms involved in the action of gabapentin for neuropathic pain are: reduction of glutamate-dependent neuronal death, increasing GABA synthesis, inhibition of monoamine …

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Preliminary studies suggest that gabapentin is associated with α 2 -δ-subunit of voltage-dependent calcium channels and inhibits the flow of calcium ions, which plays an important role in the onset of neuropathic pain.Other mechanisms involved in the action of gabapentin for neuropathic pain are: reduction of glutamate-dependent neuronal death, increasing GABA synthesis, inhibition of monoamine …

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